Associate Research Specialist role to begin in Summer 2027!
The Tsai Lab at CHLA is seeking an enthusiastic and highly motivated individual to join our research program as an Associate Research Specialist. The Tsai Lab studies the genomics of pediatric brain tumors, focusing on using functional genomics approaches to characterize tumor drivers and identify novel dependencies with the goal of finding better therapies for childhood cancer. The Associate Research Specialist will perform molecular biology techniques (cloning, plasmid generation, DNA and RNA isolations), protein work including Western blots, generate lentivirus, culture neurosphere cell lines, and perform functional genomics experiments in these cell lines. This individual will be expected to be organized, understand scientific concepts, plan and prepare for experiments, and conduct routine and non-routine laboratory procedures. This person will be expected to accurately document their methods, analyze data, and assist in the preparation of results for publication in research journals as well as posters or presentations for conferences. The candidate will present in lab meetings and will engage in one-on-one meets with the PI on a regular basis to discuss research progress and professional development, including mentorship regarding graduate and/or medical school. Additional laboratory responsibilities include ordering lab supplies, lab maintenance, and lab management.
Minimum Qualifications/Work Experience: 1+ year of experience performing independent laboratory research experiment at the time of start. Strong preference for 2 year commitment. Must be proficient in the following:
– Experience with cell culture and sterile technique
– General molecular biology skills (cloning of plasmids, lentiviral generation) and ability to follow wet lab protocols, including Western blots, PCR, DNA/RNA extractions, CRISPR/Cas9, viability assays, and drug plating
– Attention to detail and maintaining accurate records
– Ability to read and grasp scientific literature
– Curiosity and willingness to learn with excellent problem solving and decision-making skills
Education/Licensure/Certification: A Bachelors’ degree, in a related scientific field (e.g., biology, microbiology, biochemistry, chemistry, engineering)